La Liga’s quintet of Champions League representatives have made a mixed start to their respective campaigns in UEFA’s top club competition.

Real Madrid have an unblemished record after two games, but each of Spain’s other top flight clubs have lost at least once in their first couple of outings.

French international striker Kylian Mbappe has made a flying start in the competition, scoring five goals across fixtures against Marseille and Kairat Almaty.

Hie form has impressed bookmakers and Spreadex have tipped him to hit a mark of 11.9 to 12.4 goals in their season goals predictions for the Champions League.

Read on as we look at the league phase results and fixtures for La Liga’s five Champions League clubs, before assessing who will make it through to the knockout phase.

Champions League 2025-26 – La Liga clubs results & fixtures

• Athletic Club: Arsenal (L 2-0), Borussia Dortmund (L 4-1), Qarabag (H), Newcastle United (A), Slavia Prague (A), Paris Saint-Germain (H), Atalanta (A), Sporting CP (H).
• Atletico Madrid: Liverpool (L 3-2), Eintracht Frankfurt (W 5-1), Arsenal (A), Union Siant-Gilloise (H), Inter Milan (H), PSV Eindhoven (A), Galatasaray (A), Bodo/Glimt (H).
• Barcelona: (W 2-1), Paris Saint-Germain (L 2-1), Olympiacos (H), Club Brugge (A), Chelsea (A), Eintracht Frankfurt (H), Slavia Prague (A), FC Copenhagen (H).
• Real Madrid: Marseille (W 2-1), Kairat Almaty (W 5-0), Juventus (H), Liverpool (A), Olympiacos (A), Manchester City (H), Monaco (H), Benfica (A).
• Villarreal: Tottenham Hotspur (L 1-0), Juventus (D 2-2), Manchester City (H), Pafos (A), Borussia Dortmund (A), FC Copenhagen (H), Ajax (H), Bayer Leverkusen (A).

Champions League 2025-26: Madrid & Barca fancied for top eight finish

Madrid have given themselves a solid foundation to work from in the Champions League and look a good bet to progress automatically to the knockout stage.

They face Liverpool (A) and Manchester City (H) in their remaining six league phase fixtures, but the rest of their schedule looks relatively favourable.

Sixteen points was enough to secure a top eight finish last season and Madrid are already well on their way to achieving that tally.

Barcelona should also secure a place in the last-16, despite slipping to a 2-1 home defeat against reigning champion Paris Saint-Germain in their most recent outing.

A trip to Club World Cup winners Chelsea on Matchday 5 is as tough as it gets for Barcelona in their remaining fixtures and they are strongly fancied to finish in the top eight.

Atletico Madrid could also secure automatic progression to the last 16 if they can avoid defeat at Arsenal in their next fixture.

The composition of Atletico’s remaining matches gives them every chance of finishing in the top eight for the second successive season.

Villarreal face an uphill battle to qualify for the knockout stage after collecting just one point form their fixtures against Tottenham Hotspur and Juventus.

Matches against Manchester City (H), Borussia Dortmund (A) and Bayer Leverkusen (A) will test their mettle and they could miss out on finishing inside the top 24.

Athletic are also on the back foot after suffering defeats against Arsenal and Dortmund in their first two league phase outings.

They are the bookmakers’ favourites to defeat Qarabag in their next outing, despite their opponents boasting a perfect record after two games.

Each of their other five fixtures are potential banana skins and Athletic look destined to make an early exit from the competition.